Looks like the old dog can still run with the young pups. If you are starting a new web project in Python, Flask is worth a look. I spent some time poking around at the source code and it looks decent. The "context" hacks are probably the ugliest part of it but not so bad. I don't care for Django, it's origin as a content delivery system is pretty apparent.
BTW, Durus has been doing NoSQL for ages, almost as long as ZODB. :-)